Publications

  1. Holler CJ, Taylor G, McEachin ZT, Deng Q, Watkins WJ, Hudson K, Easley CA, Hu WT, Hales CM, Rossoll W, Bassell GJ, Kukar T. Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia. Mol Neurodegener. 2016 Jun 24;11(1):46. doi: 10.1186/s13024-016-0114-3. PMID: 27341800
  2. Easley IV CA, Bradner JM, Moser A, Rickman CA, McEachin ZT, Merritt M, Hansen JM and Caudle WM. Assessing Reproductive Toxicity of Environmental Toxicants with a Novel in vitro Human Spermatogenic Model. Stem Cell Res. 2015 Mar 25;14(3):347-355. doi: 10.1016/j.scr.2015.03.002. PMID: 25863443
  3. Gokhale A, Mullin AP, Zlatic SA, Easley IV CA, Merritt ME, Raj N, Larimore J, Gordon DE, Peden AA, Sanyal S and Faundez V. NSF Acts Downstream of the Schizophrenia Susceptibility Factor, Dysbindin, to Regulate Synaptic Homeostasis. J Neurosci. 2015 May 13;35(19):7643-53. doi: 10.1523/JNEUROSCI.4724-14.2015. PMID: 25972187
  4. Easley IV CA, Simerly CR, Schatten GP. Gamete derivation from embryonic stem cells, induced pluripotent stem cells or somatic cell nuclear transfer-derived embryonic stem cells: state of the art. Reprod Fertil Dev. 2014 Dec;27(1):89-92. doi: 10.1071/RD14317. PMID: 25472048
  5. Nguyen DC, Hookway TA, Wu Q, Jha R, Preininger MK, Chen X, Easley CA, Spearman P, Deshpande SR, Maher K, Wagner MB, McDevitt TC and Xu C. Microscale Generation of Cardiospheres Promotes Robust Enrichment of Cardiomyocytes Derived from Human Pluripotent Stem Cells. Stem Cell Reports. Published online July 3 2014. DOI: http://dx.doi.org/10.1016/j.stemcr.2014.06.002
  6. Sherman SL, Curnow EC, Easley CA, Jin P, Hukema RK, Tejada MI, Willemsen R, Usdin K. Use of model systems to understand the etiology of fragile X-associated primary ovarian insufficiency (FXPOI). J Neurodev Disord. 2014;6(1):26. doi: 10.1186/1866-1955-6-26. Epub 2014 Aug 13. PMID: 25147583. PMCID: PMC4139715
  7. Easley IV CA, Simerly CR and Schatten GP. Direct Differentiation of Human Pluripotent Stem Cells into Advanced Spermatogenic Cells: In Search of an in vitro System to Model Male Factor Infertility. Springer Publication Proceedings for Virginia State University STEAM-H. Accepted Feb. 2014
  8. Easley IV CA, Latov DR, Simerly CR and Schatten GP. Adult Somatic Cells to the Rescue: Nuclear Reprogramming and the Dispensability of Gonadal Germ Cells. Invited Review. Fertility and Sterility. Fertil Steril. 2014 Jan;101(1):14-9. doi: 10.1016/j.fertnstert.2013.11.025. PMID: 24382340
  9. Easley IV CA, Simerly CR, Schatten G. Stem Cell Therapeutic Possibilities: Future Therapeutic Options for Male-factor and Female-factor Infertility? Reprod Biomed Online. 2013 Mar 26. doi:pii: S1472-6483(13)00129-6.10.1016/j.rbmo.2013.03.003. [Epub ahead of print] PMID: 23664220
  10. Easley IV CA, Phillips BT, Wu G, Schatten GP, and Simerly CR. Clinical Implications of Human Spermatogenesis Initiation In Vitro. Invited Review. Oct. 2012. Journal of Medical Sciences.
  11. Easley IV CA, Phillips BT, McGuire, MM, Barringer JM, Valli H, Hermann BP, Simerly CR, Miki T, Orwig KE, and Schatten GP. Direct Differentiation of Human Pluripotent Stem Cells into Haploid Spermatogenic Cells. Online, Aug 2012, print edition Sept 2012. Cell Reports.
  12. Easley IV CA*, Miki T*, Castro CA, Ozolek JA, Minervini CF, Ben-Yehudah A and Schatten GP. Human Amniotic Epithelial Cells are Reprogrammed More Efficiently by Induced Pluripotency than Adult Fibroblasts. Cellular Reprogramming. 2012 Jun;14(3): 193-203.
  13. Shweiki D, Ben-Yehudah A, Redinger C, Easley IV C, Doron S, and Schatten G. Sexually Dimorphic Gene Expression in Non-human Primate ESCs. Biochemical and Biophysical Research Communications. 2011 Oct 28;414(3) 631-634.
  14. Varum S, Rodrigues A, Moura M, Momcilovic O, Easley C, Ramalho-Santos J, Van Houten B and Schatten G. Energetic Metabolism of Human Pluripoten Stem Cells and Their Differentiated Counterparts. PLoS ONE. 2011:6(6): e20914.
  15. Momcilovic O, Knoblach L, Fornsaglio J, Varum S, Easley C, Schatten J. DNA Damage Responses in Human Induced Pluripotent Stem Cells and Embryonic Stem Cells. PLoS One 2010 Oct 15:5(10):e13410
  16. Ben-Yehudah A, Easley IV CA, Hermann B, Castro C, Simerly C, Orwig K, Mitalopov S, Schatten G. System Biology Discoveries Using Non-Human Primate Pluripotent Stem and Germ Cells:  Novel Gene and Genomic Imprinting Interactions As Well As Unique Expression Patterns. Stem Cell Research and Therapy 2010 Aug 5;1(3):24.
  17. Easley IV CA, Ben-Yehudah A, Redinger CJ, Oliver SL, Varum ST,  Eisinger V, Carlisle D, Donovan PJ and Schatten GP. mTOR-mediated Activation of p70 S6K Induces Differentiation of Pluripotent Human Embryonic Stem Cells. Cellular Reprogramming 2010 12;3.
  18. Rothschild SC, Easley CA, Francescatto L, Lister JA, Garrity DM and Tombes RM. Tbx5-mediated β2 CaMK-II Expression is Required for Heart Looping and Pectoral Fin Development. Dev Biol. 2009 Jun 1;330(1):175-84. Epub 2009 Apr 1.
  19. Easley CA, Brown CM, Horwitz AF and Tombes RM. CaMK-II Promotes Focal Adhesion Turnover and Cell Motility by Inducing Tyrosine Dephosphorylation of FAK and Paxillin. Cell Mot. And Cyto. 2008 Aug; 65(8); 662-674.
  20. Seward ME, Easley CA, McLeod JJ, Myers AL and Tombes RM. Flightless-I, a Gelsolin Family Member and Transcriptional Regulator, Preferentially Binds Directly to Activated Cytosolic CaMK-II. FEBS Letters. 2008 Jul 23; 582(17); 2489-2495.
  21. Easley CA, Faison MO, Kirsch TL, Lee JA, Seward ME and Tombes RM. Laminin Activates CaMK-II to Stabilize Nascent Embryonic Axons. Brain Res. 2006 May 30: 1092(1); 59-68.