Work in the Easley Lab focuses on three major themes: 1) Impacts of Environmental Exposures on Human Spermatogenesis, 2) Regenerative Medicine, and 3) Drug Discovery. The Easley lab primarily uses human pluripotent stem cells and our novel in vitro model of spermatogenesis to examine the effects of environmental exposures on spermatogenesis and identify potential male contraceptives. In our regenerative medicine portfolio, we use non-human primate pluripotent stem cells as a platform to begin deriving stem cell-based therapies for future development of treatments for male factor infertility.