News
How chemical exposures can be passed from fathers to kid
Recently published in Nature Reviews Urology, researchers at the University of Georgia capture the growing evidence that paternal preconception exposures can matter a lot to offspring health. In their review, Dr. Katherine Greeson, Krista Crow, Clayton Edenfield, and Dr. Easley describe current research on paternal preconception exposures and provide a direction for future studies.
COVID-19 and Sex: What Men Need to Know
In an interview conducted by Everyday Health’s Kaitlin Sullivan, Dr. Easley at the University of Georgia discusses the impact of COVID-19 on male fertility.
Researchers suggest severe COVID-19 infection could reduce male fertility
In an interview conducted by GPB’s Ellen Eldridge, researchers at the University of Georgia discuss their newly published research about COVID-19’s effect on male fertility.
Severe COVID could Reduce Male Fertility
Recently published in Nature Reviews Urology, researchers at the University of Georgia explore how SARS-Cov-2 might target and infect testicular cells. In their review, Clayton Edenfield and Dr. Easley provide an experimental framework for tracking how the virus can impact testicular function and fertility in patients with acute COVID-19 infection.
Seeking Solutions for Male Infertility
As the rates of male factor infertility continue to rise across Western countries, a team of scientists, including undergraduate and graduate students, postdoctoral researchers, a research coordinator, and a lab manager, Dr. Easley, is conducting research that offers hope to couples who are struggling with infertility. His work also has the potential to help keep reproductive toxicants out of products that millions of people use daily.
Read more from the UGA College of Public Health Magazine 2021 Issue…
Using Skin Cells to Treat Infertility
For the first time, research led by Dr. Easley showed that rhesus macaque spermatid-like cells generated in a dish from macaque embryonic stem cells could successfully fertilize a macaque egg. This research was featured in an interview with UGA Research.
A New Breakthrough for Treatment of Male Infertility
Embryonic stem cells from rhesus macaque monkeys were used to generate round spermatids, immature sperm cells, that were capable of fertilizing a macaque egg. Led by researchers from the University of Georgia, Oregon National Primate Research Center, and the University of Pittsburgh, this research, recently published in Fertility & Sterility, is a major breakthrough to use stem cell-based technologies to treat male infertility in cases where these men do not produce any viable sperm cells.
Researchers Developing New Therapy to Address Male Sterility
Researchers from the University of Georgia, Emory University School of Medicine, and the University of Pittsburgh have received a $2.9 million grant from the National Institutes of Health to test a novel method of producing viable sperm cells from skin cells.
Flame Retardants May Affect Future Generations Via Changes in Sperm
NIEHS grantees reported that exposure to polybrominated biphenyl (PBB) 153, a type of brominated flame retardant, alters DNA methylation in sperm. DNA methylation refers to heritable changes in gene expression that occur with no alteration to the DNA sequence. PBB153 is known to be toxic to those who are directly exposed. The new study indicates that exposure may also harm future generations.
Human Spermatogenic Cells from Pluripotent Stem Cells including eventually Patient-Specific iPSCs
Researchers report that human pluripotent stem cells can be directly differentiated in haploid spermatogenic cells, immature sperm cells.
Creating Sperm from Skin
Men made infertile by cancer treatments could have their fertility restored by creating new sperm from their own skin samples, researchers at the University of Pittsburgh School of Medicine reported in Cell Reports.
Sperm precursor cells are grown from a skin sample
Stem cells found in human skin can be turned into sperm precursor cells, US researchers have found. The findings could help restore fertility to cancer patients and could provide a new way of studying the development of sperm cells in the lab.
Dream of fatherhood for thousands of infertile men a step closer as scientists ‘grow’ sperm from skin
Scientists have succeeded in making early-stage sperm from human skin tissue. The technique could potentially help thousands of infertile men, including survivors of childhood cancer, fulfill their dream of fatherhood.